Comparison of Tc-99m sestamibi perfusion imaging and echocardiography using an arbutamine infusion for the detection of coronary artery disease

Am J Cardiol. 1997 Jun 1;79(11):1518-21. doi: 10.1016/s0002-9149(97)00183-5.

Abstract

Arbutamine, a synthetic catecholamine, coupled with a closed-loop, computerized delivery system was evaluated in conjunction with technetium-99m sestamibi scintigraphy and echocardiography for the detection of coronary artery disease. Concordance between the imaging methods was 68%, with a similar sensitivity for coronary disease using echocardiography (78%) and technetium-99m sestamibi (76%), although more arbutamine-induced ischemia was noted with perfusion imaging.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adrenergic beta-Agonists*
  • Catecholamines*
  • Coronary Disease / diagnostic imaging*
  • Coronary Vessels / diagnostic imaging
  • Diagnosis, Differential
  • Echocardiography / methods*
  • Humans
  • Predictive Value of Tests
  • Radionuclide Imaging
  • Radiopharmaceuticals*
  • Sensitivity and Specificity
  • Technetium Tc 99m Sestamibi*

Substances

  • Adrenergic beta-Agonists
  • Catecholamines
  • Radiopharmaceuticals
  • Technetium Tc 99m Sestamibi
  • arbutamine