Aminoguanidine inhibits the generation of nitric oxide in vitro and prolongs islet xenograft survival in rats

Transplant Proc. 1997 Jun;29(4):2152-3. doi: 10.1016/s0041-1345(97)00270-4.
No abstract available

MeSH terms

  • Analysis of Variance
  • Animals
  • Diabetes Mellitus, Experimental / blood
  • Diabetes Mellitus, Experimental / surgery
  • Enzyme Inhibitors / pharmacology*
  • Gamma Rays
  • Graft Survival / drug effects*
  • Guanidines / pharmacology*
  • Humans
  • Islets of Langerhans / cytology
  • Islets of Langerhans / physiology*
  • Islets of Langerhans / radiation effects
  • Islets of Langerhans Transplantation / physiology*
  • Male
  • Nitric Oxide / metabolism*
  • Nitric Oxide Synthase / antagonists & inhibitors
  • Nitric Oxide Synthase / biosynthesis*
  • Polymerase Chain Reaction
  • Rats
  • Rats, Wistar
  • Transcription, Genetic / drug effects
  • Transplantation, Heterologous / physiology*

Substances

  • Enzyme Inhibitors
  • Guanidines
  • Nitric Oxide
  • Nitric Oxide Synthase
  • pimagedine