Association of visual field, cup-disc ratio, and magnetic resonance imaging of optic chiasm

Arch Ophthalmol. 1997 Jun;115(6):729-32. doi: 10.1001/archopht.1997.01100150731006.

Abstract

Objective: To assess the association of visual field, vertical cup-disc (VC/D) ratio, and vertical height of optic chiasm.

Design: Case series.

Setting: Outpatient eye clinic.

Patients: Eighteen patients with low, normal, or elevated intraocular pressure, with or without visual field defects.

Intervention: Measurement of visual field, VC/D ratio, and vertical height of optic chiasm.

Main outcome measures: Association between VC/D ratio and visual field defects compared with association between vertical height of optic chiasm and visual field defects.

Results: Visual field defects were graded as 0, 1 to 10, and 11 to 20 (from least to most severe). Group mean VC/D ratios were 0.47 (0), 0.55 (1-10), and 0.69 (11-20) for right eyes and 0.48 (0), 0.57 (1-10), and 0.75 (11-20) for left eyes. The significance level for trend was P = .02 for right eyes and P = .006 for left eyes. Group mean chiasm heights were 3.5 (0), 2.9 (1-10), and 2.2 (11-20) mm for right eyes and 3.5 (0), 2.8 (1-10), and 2.2 (11-20) mm for left eyes. The significance level for trend was P < .001 for right eyes and P = .002 for left eyes. To assess the simultaneous effects of VC/D ratio and chiasm height on the visual field defects groups, we used ordinal logistic regression models. Models with both variables implied that chiasm height was a stronger predictor of visual field defects group than VC/D ratio (for right eyes, P = .04 [VC/D ratio], P = .001 [chiasm height]; for left eyes, P = .11 [VC/D ratio], P = .005 [chiasm height]).

Conclusions: When chiasm and VC/D ratio were analyzed in the same model, chiasm height was a stronger predictor of visual field defects. In advanced visual field defects, the optic chiasm is atrophic.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Female
  • Glaucoma / diagnosis*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Optic Chiasm / pathology*
  • Optic Disk / pathology*
  • Predictive Value of Tests
  • Regression Analysis
  • Vision Disorders / diagnosis*
  • Visual Fields*