Reproducibility of MEG auditory evoked field source localizations in normal human subjects using a seven-channel gradiometer

IEEE Trans Biomed Eng. 1996 Sep;43(9):967-9. doi: 10.1109/10.532131.

Abstract

Magnetoencephalographic (MEG) auditory evoked fields (EF) were recorded from 12 normal adult subjects over both hemispheres on two separate occasions at least one week apart using a seven-channel second-order gradiometer. Stimuli were computer-generated at 25-msec duration, 1 kHz tone pips. Responses to 100 stimuli were averaged, and source estimates with confidence intervals were computed, for the 100-msec latency auditory EF component, termed M100. Root-mean-squared (rms) differences in x, y, and z locations were approximately 0.7 cm on the two occasions; strength and orientation differences were 18 nA-m and 11 degrees, respectively. This spatial accuracy using a seven-channel instrument, compares favorably with other currently available technologies for localization of brain function.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Analysis of Variance
  • Confidence Intervals
  • Evoked Potentials, Auditory*
  • Female
  • Humans
  • Magnetoencephalography / standards*
  • Male
  • Reference Values
  • Reproducibility of Results