The phonological loop in medicated patients with Parkinson's disease: presence of phonological similarity and word length effects

J Neurol Neurosurg Psychiatry. 1997 Jun;62(6):609-11. doi: 10.1136/jnnp.62.6.609.

Abstract

Objective: To test the verbal subsystem of Baddeley's working memory model (the phonological loop) in patients with Parkinson's disease.

Methods: Fifteen patients with idiopathic Parkinson's disease and 15 controls were tested with a span paradigm to assess the effects reflecting the functioning of the phonological loop: the phonological similarity effect (in verbal and visual presentation), and the word length effect (in visual presentation).

Results and conclusions: The patients did not show any dysfunction of the phonological loop, reflected by the presence of phonological similarity and word length effects, but had lower spans than controls. The implications of these results for the working memory model are discussed.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Antiparkinson Agents / pharmacology*
  • Antiparkinson Agents / therapeutic use*
  • Dopamine Agonists / pharmacology*
  • Dopamine Agonists / therapeutic use*
  • Female
  • Frontal Lobe / drug effects
  • Humans
  • Language Tests
  • Levodopa / pharmacology*
  • Levodopa / therapeutic use*
  • Male
  • Memory / drug effects
  • Parkinson Disease / drug therapy*
  • Phonetics*
  • Piribedil / pharmacology*
  • Piribedil / therapeutic use*
  • Severity of Illness Index
  • Verbal Behavior / drug effects*

Substances

  • Antiparkinson Agents
  • Dopamine Agonists
  • Levodopa
  • Piribedil