Induction of cytochrome P450 in Hep G2 cells and mutagenicity of extracts of sediments from a waste disposal site near Osaka, Japan

Bull Environ Contam Toxicol. 1997 Sep;59(3):344-51. doi: 10.1007/s001289900484.
No abstract available

MeSH terms

  • 7-Alkoxycoumarin O-Dealkylase / biosynthesis
  • Anthracenes / analysis
  • Benzo(a)pyrene / analysis
  • Carcinoma, Hepatocellular
  • Chromatography, High Pressure Liquid
  • Cytochrome P-450 Enzyme System / biosynthesis*
  • Environmental Pollutants / analysis
  • Environmental Pollutants / toxicity*
  • Enzyme Induction / drug effects
  • Fluorenes / analysis
  • Gene Expression Regulation, Enzymologic / drug effects
  • Hazardous Waste / adverse effects*
  • Hazardous Waste / analysis
  • Humans
  • Japan
  • Liver Neoplasms
  • Mutagenicity Tests
  • Polycyclic Aromatic Hydrocarbons / analysis*
  • Pyrenes / analysis
  • Tumor Cells, Cultured / drug effects
  • Tumor Cells, Cultured / enzymology
  • Water Pollutants, Chemical / analysis
  • Water Pollutants, Chemical / toxicity*

Substances

  • Anthracenes
  • Environmental Pollutants
  • Fluorenes
  • Hazardous Waste
  • Polycyclic Aromatic Hydrocarbons
  • Pyrenes
  • Water Pollutants, Chemical
  • Benzo(a)pyrene
  • fluoranthene
  • Cytochrome P-450 Enzyme System
  • pyrene
  • 7-Alkoxycoumarin O-Dealkylase
  • anthracene