HMG-CoA reductase inhibitor suppression of glomerular cell proliferation in rats with anti-Thy-1.1 nephritis

Contrib Nephrol. 1997:120:153-9. doi: 10.1159/000059834.

Authors

K Nabeshima¹, K Inui, S Uda, Y Sugenoya, S Iwasaki, T Ideura, A Yoshimura

Affiliation

¹ Department of Internal Medicine, Showa University Fujigaoka Hospital, Yokohama, Japan.

PMID: 9257058
DOI: 10.1159/000059834

No abstract available

MeSH terms

Actins / biosynthesis
Animals
Cell Division / drug effects
Cells, Cultured
Glomerular Mesangium / drug effects
Glomerular Mesangium / metabolism
Glomerular Mesangium / pathology*
Glomerulonephritis / immunology
Glomerulonephritis / metabolism
Glomerulonephritis / pathology*
Hydroxymethylglutaryl-CoA Reductase Inhibitors / pharmacology*
Immunohistochemistry
Isoantibodies / immunology*
Lovastatin / analogs & derivatives*
Lovastatin / pharmacology
Macrophages / immunology
Male
Muscle, Smooth / chemistry
Rats
Rats, Wistar
Simvastatin

Substances

Actins
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Isoantibodies
anti-Thy antibody
Lovastatin
Simvastatin