Predictive factors of callosotomy in drug-resistant epileptic patients with a long follow-up

J Neurosurg Sci. 1997 Mar;41(1):31-6.

Abstract

Some possible factors to predict outcome after callosotomy were investigated in a personal series composed of 36 patients. Twenty-seven of them were submitted to anterior callosotomy, 1 to posterior callosotomy and the remaining 8 patients to two stage complete division of corpus callosum. All factors, either positive or negative, do not appear completely reliable; they can be envisaged only in relative terms and do not seem to be relevant to make surgical decision or to discard surgery. In author's series, dealing specifically with drop-attacks, it clearly appeared that abrupt falls to the ground unpreceded by other epileptic features did definitely better. This was the only statistically significant datum.

MeSH terms

  • Adolescent
  • Adult
  • Corpus Callosum / surgery*
  • Drug Resistance
  • Epilepsy / surgery*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Risk Factors
  • Time Factors