IL-10 prevents the generation of dendritic cells from CD14+ blood monocytes, promotes the differentiation to mature macrophages and stimulates endocytosis of FITC-dextran

Adv Exp Med Biol. 1997:417:323-7. doi: 10.1007/978-1-4757-9966-8_53.

Authors

P Allavena¹, L Piemonti, D Longoni, S Bernasconi, A Stoppacciaro, L Ruco, A Mantovani

Affiliation

¹ Department of Immunology and Cell Biology, Mario Negri Institute, Milano, Italy.

PMID: 9286381
DOI: 10.1007/978-1-4757-9966-8_53

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cell Differentiation / drug effects
Dendritic Cells / cytology*
Dendritic Cells / drug effects
Dendritic Cells / immunology*
Dextrans
Endocytosis / drug effects
Fetal Blood / cytology
Fetal Blood / immunology
Fluorescein-5-isothiocyanate / analogs & derivatives
Humans
In Vitro Techniques
Infant, Newborn
Interleukin-10 / pharmacology*
Lipopolysaccharide Receptors / metabolism
Macrophages / cytology*
Macrophages / drug effects
Macrophages / immunology*
Monocytes / cytology*
Monocytes / drug effects
Monocytes / immunology*
Tumor Necrosis Factor-alpha / pharmacology

Substances

Dextrans
Lipopolysaccharide Receptors
Tumor Necrosis Factor-alpha
fluorescein isothiocyanate dextran
Interleukin-10
Fluorescein-5-isothiocyanate