Simultaneous occurrence of papulonecrotic tuberculide and erythema induratum and the identification of Mycobacterium tuberculosis DNA by polymerase chain reaction

Br J Dermatol. 1997 Aug;137(2):276-81. doi: 10.1046/j.1365-2133.1997.18201916.x.

Abstract

The simultaneous occurrence of two tuberculides in one patient is rare. We report the case of a 32-year-old man presenting with both papulonecrotic tuberculide and erythema induratum. Mycobacterial DNA was identified from both skin lesions by polymerase chain reaction using formalin-fixed and paraffin-embedded tissues, suggesting that tuberculides are related to tuberculosis. New skin lesions developed after the patient discontinued his medication on his own initiative, 2 months after triple antituberculous therapy had been started. It is important to continue therapy for a prolonged period.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • DNA, Bacterial / analysis
  • Erythema Induratum / complications
  • Erythema Induratum / microbiology
  • Erythema Induratum / pathology
  • Humans
  • Male
  • Mycobacterium tuberculosis / genetics
  • Mycobacterium tuberculosis / isolation & purification*
  • Polymerase Chain Reaction
  • Tuberculosis, Cutaneous / complications
  • Tuberculosis, Cutaneous / microbiology
  • Tuberculosis, Cutaneous / pathology*

Substances

  • DNA, Bacterial