Abstract
Recent knowledge of the composition of coronary plaques is briefly reviewed, including factors that are considered to be responsible for the provocation of instability. Based on this information, possibilities for the early detection of threatening instability and measures to prevent destabilization of coronary plaques and to counteract thrombus formation are discussed.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Collagen / metabolism
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Coronary Artery Disease / complications
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Coronary Artery Disease / drug therapy
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Coronary Artery Disease / physiopathology*
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Coronary Artery Disease / therapy*
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Coronary Thrombosis / etiology
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Coronary Thrombosis / physiopathology
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Coronary Thrombosis / prevention & control
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Humans
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Inflammation Mediators / physiology
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Macrophage Activation
Substances
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Inflammation Mediators
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Collagen