GAPO syndrome: first Egyptian case with ultrastructural changes in the gingiva

N A Meguid; H H Afifi; M I Ramzy; A Hindawy; S A Temtamy

doi:10.1111/j.1399-0004.1997.tb02527.x

GAPO syndrome: first Egyptian case with ultrastructural changes in the gingiva

Clin Genet. 1997 Aug;52(2):110-5. doi: 10.1111/j.1399-0004.1997.tb02527.x.

Authors

N A Meguid¹, H H Afifi, M I Ramzy, A Hindawy, S A Temtamy

Affiliation

¹ Human Genetics Department, National Research Centre, Cairo, Egypt.

PMID: 9298746
DOI: 10.1111/j.1399-0004.1997.tb02527.x

Abstract

We report on a 3-year-old boy with growth retardation, alopecia, pseudoanodontia, and optic atrophy. This is the 18th known and the first Egyptian case of GAPO syndrome. Electron microscopic examination of gingival biopsy showed excessive collagen fibres and endothelial vacuolisation, suggesting involvement of extracellular pathological collagenosis.

Publication types

Case Reports

MeSH terms

Abnormalities, Multiple / diagnostic imaging
Abnormalities, Multiple / pathology*
Alopecia* / pathology
Anodontia / diagnostic imaging*
Anodontia / pathology
Child, Preschool
Egypt
Gingiva / diagnostic imaging
Gingiva / ultrastructure*
Growth Disorders* / pathology
Humans
Magnetic Resonance Imaging
Male
Optic Atrophy* / diagnostic imaging
Optic Atrophy* / pathology
Radiography
Syndrome