Effectiveness of selective neck dissection for management of the clinically negative neck

Arch Otolaryngol Head Neck Surg. 1997 Sep;123(9):917-22. doi: 10.1001/archotol.1997.01900090023004.

Abstract

Objective: To determine the effectiveness of selective neck dissection for management of the clinically negative neck in head and neck squamous cell carcinoma.

Design: A retrospective comparison of patients treated electively with selective neck dissection and comprehensive neck dissection.

Setting: Academic tertiary referral center.

Patients: Patients with clinically negative necks and previously untreated head and neck squamous cell carcinoma.

Intervention: Elective neck dissection, surgical treatment of the primary lesion, and postoperative radiotherapy as indicated.

Outcome measures: Regional recurrence, distant metastasis, and disease-free survival.

Results: Selective neck dissection was as effective as comprehensive procedures for staging the clinically negative neck. Occult metastases had a statistically significant effect on patient outcome as measured by distant metastasis.

Conclusion: Elective neck dissection provides invaluable staging information, which guides the decision for adjuvant therapy.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Antidotes / administration & dosage
  • Antimetabolites, Antineoplastic / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / secondary
  • Carcinoma, Squamous Cell / surgery*
  • Chemotherapy, Adjuvant
  • Decision Making
  • Disease-Free Survival
  • Elective Surgical Procedures
  • Fluorouracil / administration & dosage
  • Follow-Up Studies
  • Head and Neck Neoplasms / pathology
  • Head and Neck Neoplasms / surgery*
  • Humans
  • Leucovorin / administration & dosage
  • Lymph Node Excision* / classification
  • Lymph Nodes / pathology
  • Methotrexate / administration & dosage
  • Middle Aged
  • Neck
  • Neck Dissection / classification
  • Neoplasm Recurrence, Local / pathology
  • Neoplasm Staging
  • Radiotherapy, Adjuvant
  • Retrospective Studies
  • Treatment Outcome

Substances

  • Antidotes
  • Antimetabolites, Antineoplastic
  • Leucovorin
  • Fluorouracil
  • Methotrexate