Inactivation of prostaglandin endoperoxide synthase (PGHS) by N-(substituted)maleimides

Adv Exp Med Biol. 1997:407:79-85. doi: 10.1007/978-1-4899-1813-0_12.
No abstract available

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Caprylates / pharmacology
  • Cyclooxygenase Inhibitors / chemistry
  • Cyclooxygenase Inhibitors / pharmacology*
  • Humans
  • Maleimides / chemistry
  • Maleimides / pharmacology*
  • Peroxidases / antagonists & inhibitors
  • Prostaglandin-Endoperoxide Synthases / drug effects*
  • Substrate Specificity
  • Trypsin / pharmacology

Substances

  • Caprylates
  • Cyclooxygenase Inhibitors
  • Maleimides
  • N-(carboxyheptyl)maleimide
  • Peroxidases
  • Prostaglandin-Endoperoxide Synthases
  • Trypsin