TNF alpha-dependent induction of cyclooxygenase-2 mediated by NF kappa B and NF-IL6

Adv Exp Med Biol. 1997:407:185-9.

Authors

K Yamamoto¹, T Arakawa, Y Taketani, Y Takahashi, Y Hayashi, N Ueda, S Yamamoto, M Kumegawa

Affiliation

¹ Department of Biochemistry, University of Tokushima School of Medicine, Japan.

PMID: 9321951

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
CCAAT-Enhancer-Binding Proteins
Cell Line
Cyclooxygenase 2
DNA-Binding Proteins / physiology*
Dinoprostone / metabolism
Enzyme Induction / drug effects
Genes, Reporter
Isoenzymes / biosynthesis*
Isoenzymes / genetics
Mice
Models, Biological
NF-kappa B / physiology*
Nuclear Proteins / physiology*
Promoter Regions, Genetic
Prostaglandin-Endoperoxide Synthases / biosynthesis*
Prostaglandin-Endoperoxide Synthases / genetics
Recombinant Fusion Proteins / biosynthesis
Signal Transduction / physiology
Skull / cytology
Transcription, Genetic / drug effects*
Tumor Necrosis Factor-alpha / pharmacology*

Substances

CCAAT-Enhancer-Binding Proteins
DNA-Binding Proteins
Isoenzymes
NF-kappa B
Nuclear Proteins
Recombinant Fusion Proteins
Tumor Necrosis Factor-alpha
Cyclooxygenase 2
Prostaglandin-Endoperoxide Synthases
Dinoprostone