Examination of ligand-induced conformational changes in the beta 2-adrenergic receptor by fluorescence spectroscopy

Adv Pharmacol. 1998:42:470-3. doi: 10.1016/s1054-3589(08)60790-5.
No abstract available

MeSH terms

  • Adenylyl Cyclases / metabolism
  • Adrenergic beta-Agonists / pharmacology
  • Adrenergic beta-Antagonists / pharmacology
  • Animals
  • Cell Line
  • Cysteine
  • Epinephrine / pharmacology*
  • Fluorescent Dyes
  • Isoproterenol / pharmacology*
  • Ligands
  • Mutagenesis
  • Oxadiazoles
  • Propanolamines / pharmacology
  • Propranolol / pharmacology
  • Protein Conformation* / drug effects
  • Receptors, Adrenergic, beta-2 / biosynthesis
  • Receptors, Adrenergic, beta-2 / chemistry*
  • Receptors, Adrenergic, beta-2 / drug effects
  • Recombinant Proteins / biosynthesis
  • Recombinant Proteins / chemistry
  • Spectrometry, Fluorescence / methods
  • Spodoptera
  • Transfection

Substances

  • Adrenergic beta-Agonists
  • Adrenergic beta-Antagonists
  • Fluorescent Dyes
  • Ligands
  • Oxadiazoles
  • Propanolamines
  • Receptors, Adrenergic, beta-2
  • Recombinant Proteins
  • ICI 118551
  • 4-(N-(iodoacetoxy)ethyl-N-methyl)amino-7-nitrobenz-2-oxa-1,3-diazole
  • Propranolol
  • Adenylyl Cyclases
  • Cysteine
  • Isoproterenol
  • Epinephrine