Abstract
A 20-month-old boy was investigated for persistent liver dysfunction. Liver histologic findings showed chronic hepatitis. The presence of human herpesvirus-6 DNA in liver tissue was demonstrated both by in situ hybridization and by polymerase chain reaction. Human herpesvirus-6 may be a causative agent of chronic hepatitis in this case.
MeSH terms
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Biopsy
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Blotting, Southern
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Chronic Disease
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DNA, Viral / analysis*
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Diagnosis, Differential
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Exanthema Subitum / complications*
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Hepatitis, Viral, Human / blood
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Hepatitis, Viral, Human / pathology
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Hepatitis, Viral, Human / virology*
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Herpesvirus 6, Human / genetics*
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Humans
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In Situ Hybridization
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Infant
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Leukocytes, Mononuclear / virology*
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Male
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Polymerase Chain Reaction