[The differentiation of adrenal gland tumors: an improvement in accuracy by a combination of fat-sensitive, T2-weighted and contrast-enhanced MR sequences]

Rofo. 1997 Aug;167(2):153-9. doi: 10.1055/s-2007-1015509.
[Article in German]

Abstract

Purpose: To determine the diagnostic value of 3 MR sequences for the diagnosis of adrenal tumors.

Material and methods: Retrospective analysis of 32 adrenal tumors (10 malignant, 15 adenomas, 5 inflammatory, 2 phaeochromocytomas) examined by MRT (1.5 T) using T2 turbo spin echo, chemical shift imaging and dynamic contrast-enhanced gradient echo sequences.

Results: Differentiation between malignant and benign adrenal tumours by means of T2-weighted sequences, chemical shift imaging and dynamic contrast-enhanced sequences achieved a sensitivity/specificity of 90%/73%, 100%/68% and 90%86%. Accuracy was 78%, 78% and 87%. By combining the three procedures, sensitivity/specificity/accuracy was improved to 100%/91%/94%.

Conclusion: To differentiate adrenal lesions, the following procedures are recommended: demonstration of fat by chemical shift imaging is indicative of an adenoma. In the absence of any lipid content, T2-weighted and dynamic contrast-enhanced sequences can demonstrate inflammatory lesions.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenoma / diagnosis*
  • Adrenal Gland Diseases / diagnosis
  • Adrenal Gland Neoplasms / diagnosis*
  • Adrenal Glands / pathology
  • Carcinoma / diagnosis*
  • Contrast Media*
  • Diagnosis, Differential
  • Humans
  • Magnetic Resonance Imaging / instrumentation
  • Magnetic Resonance Imaging / methods*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Time Factors
  • Tuberculosis, Endocrine / diagnosis

Substances

  • Contrast Media