Malignant proliferating trichilemmal tumor showing distant metastases

Am J Dermatopathol. 1997 Oct;19(5):536-9. doi: 10.1097/00000372-199710000-00109.

Abstract

We describe a case of malignant proliferating trichilemmal tumor showing multiple distant metastases. For 10 years, the patient had had a round mass in the occiput, which recurred twice after wide excisions, and later metastasized to the cervical lymph nodes, periparotid area, and chest. Each time the lesions were excised, histologic specimens demonstrated a proliferating trichilemmal tumor with increasing nuclear atypia. Serial specimens showed increasing Ki-67 positivity as the extent of the tumor advanced.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cell Division
  • Cell Nucleus / ultrastructure
  • Head and Neck Neoplasms / secondary
  • Humans
  • Ki-67 Antigen / analysis
  • Lymphatic Metastasis / pathology*
  • Male
  • Neoplasm Recurrence, Local / pathology
  • Neoplasms, Basal Cell / pathology*
  • Neoplasms, Basal Cell / secondary
  • Scalp / pathology*
  • Skin Neoplasms / pathology*
  • Thoracic Neoplasms / secondary

Substances

  • Ki-67 Antigen