Terlipressin may influence the outcome of hepatorenal syndrome complicating alcoholic hepatitis

Am J Gastroenterol. 1997 Nov;92(11):2113-4.

Abstract

Hepatorenal syndrome is a frequent complication associated with extremely short survival in cirrhotic patients with alcoholic hepatitis. Vasopressin analogs have been reported to induce transient regression of hepatorenal syndrome in patients with cirrhosis. However, treatment withdrawal was followed by early recurrences in every case. We report the case of a 68-yr-old woman with severe alcoholic hepatitis complicated by hepatorenal syndrome. Terlipressin induced a prolonged recovery of renal function that was associated with improvement in hepatic function.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Chronic Disease
  • Female
  • Hepatitis, Alcoholic / complications
  • Hepatitis, Alcoholic / drug therapy*
  • Hepatorenal Syndrome / drug therapy*
  • Hepatorenal Syndrome / etiology
  • Humans
  • Lypressin / analogs & derivatives*
  • Lypressin / therapeutic use
  • Remission Induction
  • Terlipressin

Substances

  • Lypressin
  • Terlipressin