DHFR gene point mutation as a predictor of Plasmodium falciparum resistance to cycloguanil in malaria cases from Africa imported to France

Trans R Soc Trop Med Hyg. 1997 Jul-Aug;91(4):460-1. doi: 10.1016/s0035-9203(97)90285-6.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antimalarials / therapeutic use*
  • Asparagine
  • Drug Resistance / genetics
  • Humans
  • Malaria, Falciparum / drug therapy*
  • Plasmodium falciparum / drug effects
  • Plasmodium falciparum / genetics*
  • Point Mutation*
  • Polymerase Chain Reaction
  • Proguanil
  • Serine
  • Tetrahydrofolate Dehydrogenase / genetics*
  • Travel
  • Triazines / therapeutic use*

Substances

  • Antimalarials
  • Triazines
  • cycloguanil
  • Serine
  • Asparagine
  • Tetrahydrofolate Dehydrogenase
  • Proguanil