[A new method of administration of budesonide powder for the treatment of allergic rhinitis]

Acta Otorrinolaringol Esp. 1997 Jun-Jul;48(5):353-7.
[Article in Spanish]

Abstract

The efficacy and safety of a new device for administering powdered budesonide in allergic rhinitis was evaluated. This method eliminates the disadvantages of traditional preparations and improves dosing and administration, even at low nasal flow rates. A randomized, controlled, single-blind study was made in 66 patients with allergic rhinitis, half of whom were assigned to the experimental treatment (powdered budesonide) and half to a standard aerosol. Results showed that both preparations were very effective (p < 0.01) in controlling rhinitis symptoms and not significantly different. However, the overall patient evaluation was significantly better (p < 0.01) in the group treated with powdered budesonide. Both treatments elicited a similar tolerance, although tolerance of powdered budesonide was slightly better. To conclude, treatment with the new powdered budesonide dispenser was as effective and well-tolerated as standard treatment, and better accepted by patients.

Publication types

  • Clinical Trial
  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Anti-Inflammatory Agents / therapeutic use*
  • Budesonide / therapeutic use*
  • Drug Tolerance
  • Female
  • Humans
  • Male
  • Powders
  • Rhinitis, Allergic, Perennial / drug therapy*

Substances

  • Anti-Inflammatory Agents
  • Powders
  • Budesonide