[How great is radiation exposure in the area surrounding patients after administration ov 99mTc-sestamibi?]

Nuklearmedizin. 1997 Sep;36(6):202-4.
[Article in German]

Abstract

Aim: The aim of the present study was to estimate the additional radiation exposure to personnel, other patients and members of the family caused by patients who had been injected with 99mTc-Sestamibi (Cardiolite DuPONT PHARMA) for preoperative localization of parathyroid adenoma.

Methods: Dose rates were measured from 16 patients who had received an intravenous injection of 600 +/- 50 MBq 99mTc-Sestamibi. All measurements were performed with a portable dosimeter (Berthold LB 133) at 3 different distances (0.5, 1 and 2 m) at 10 min, 180-200 min and 24 h after administration of the tracer.

Results: The dose rates amounted to 20.5 microSv/h at 0.5 m, 5.25 microSv/h at 1 m and 1.55 microSv/h at 2 m distance from patients respectively. The biological half-life was 54 h. The calculated maximal dose to other persons in the waiting area was 31.2 microSv, to family members 27.6 microSv and to nurses in a ward 31.2 microSv.

Conclusion: Our results indicate that the calculated maximal radiation exposure for personnel, family members and other patients even under very unfavourable conditions was below the maximal allowed dose for non-professionally exposed persons.

MeSH terms

  • Adenoma / diagnostic imaging*
  • Air Pollution, Indoor*
  • Air Pollution, Radioactive / analysis*
  • Environmental Exposure*
  • Half-Life
  • Health Personnel
  • Humans
  • Hyperparathyroidism / diagnostic imaging*
  • Hyperparathyroidism / etiology
  • Inpatients
  • Male
  • Occupational Exposure
  • Parathyroid Neoplasms / diagnostic imaging*
  • Radionuclide Imaging
  • Technetium Tc 99m Sestamibi*
  • Visitors to Patients

Substances

  • Technetium Tc 99m Sestamibi