Cytokine signaling: cytokine-inducible signaling inhibitors

M J Aman; W J Leonard

doi:10.1016/s0960-9822(06)00405-2

Cytokine signaling: cytokine-inducible signaling inhibitors

Curr Biol. 1997 Dec 1;7(12):R784-8. doi: 10.1016/s0960-9822(06)00405-2.

Authors

M J Aman¹, W J Leonard

Affiliation

¹ Laboratory of Molecular Immunology, National Institute of Health, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20893, USA.

PMID: 9382832
DOI: 10.1016/s0960-9822(06)00405-2

Abstract

Seven members of a family of cytokine-inducible proteins have been identified, a number of which have been shown to act as negative regulators of cytokine action. All of these proteins contain a central Src homology 2 domain, as well as conserved motifs in their carboxy-terminal regions.

Publication types

Review

MeSH terms

Amino Acid Sequence
Binding Sites
Cytokines / metabolism*
Humans
Immediate-Early Proteins / chemistry
Immediate-Early Proteins / metabolism*
Immediate-Early Proteins / physiology
Molecular Sequence Data
Sequence Homology, Amino Acid
Signal Transduction*
Suppressor of Cytokine Signaling Proteins
src Homology Domains*

Substances

Cytokines
Immediate-Early Proteins
Suppressor of Cytokine Signaling Proteins
cytokine inducible SH2-containing protein