Nonlinear property membrane rectifier potassium channel and inhibitory effects of oxygen free radical

Chin Med Sci J. 1996 Sep;11(3):174-6.

Abstract

There are at least eight kinds of different potassium channels on cardiac cell membrane. This paper presents a nonlinear property membrane outward current going rectifying potassium channel and the inhibitory effects of oxygen free radical on this channel. The current-voltage relation of this nonlinear-membrane can be defined by an equation I = 8a3/(0.01v2 + 4a2)2 and the maximum conductance of this channel is -75.3 pS.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Child
  • Child, Preschool
  • Female
  • Free Radicals / metabolism
  • Humans
  • Membrane Potentials
  • Oxygen / metabolism*
  • Papillary Muscles / physiology*
  • Potassium Channels / drug effects*
  • Pregnancy
  • Rats
  • Rats, Wistar

Substances

  • Free Radicals
  • Potassium Channels
  • Oxygen