Abstract
Two hundred twenty-eight patients with successful coronary stent implantation were randomized either to protamine administration and femoral sheath removal (group I, n = 117) or no heparin neutralization and delayed sheath removal (group II, n = 111). The hospital stay after treatment was shorter in patients receiving protamine; therefore, protamine use for neutralizing circulating heparin may be safely administered immediately after stent implantation.
Publication types
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Clinical Trial
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Comparative Study
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Randomized Controlled Trial
MeSH terms
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Anticoagulants / therapeutic use
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Coronary Disease / therapy*
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Dalteparin / therapeutic use
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Female
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Femoral Artery
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Hemorrhage / prevention & control
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Heparin / therapeutic use
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Heparin Antagonists / therapeutic use*
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Humans
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Male
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Middle Aged
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Premedication
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Protamines / therapeutic use*
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Stents*
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Thrombosis / prevention & control
Substances
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Anticoagulants
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Heparin Antagonists
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Protamines
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Heparin
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Dalteparin