Propofol anesthesia and rational opioid selection: determination of optimal EC50-EC95 propofol-opioid concentrations that assure adequate anesthesia and a rapid return of consciousness

Anesthesiology. 1997 Dec;87(6):1549-62. doi: 10.1097/00000542-199712000-00033.

Authors

J Vuyk¹, M J Mertens, E Olofsen, A G Burm, J G Bovill

Affiliation

¹ Department of Anaesthesiology, University Hospital Leiden, The Netherlands. [email protected]

PMID: 9416739
DOI: 10.1097/00000542-199712000-00033

No abstract available

MeSH terms

Alfentanil / pharmacokinetics
Alfentanil / pharmacology
Analgesics, Opioid / pharmacokinetics
Analgesics, Opioid / pharmacology*
Anesthesia Recovery Period
Anesthesia, Intravenous*
Anesthetics, Intravenous / pharmacokinetics
Anesthetics, Intravenous / pharmacology*
Computer Simulation
Drug Interactions
Fentanyl / pharmacokinetics
Fentanyl / pharmacology
Half-Life
Humans
Probability
Propofol / pharmacokinetics
Propofol / pharmacology*
Sufentanil / pharmacokinetics
Sufentanil / pharmacology
Time Factors

Substances

Analgesics, Opioid
Anesthetics, Intravenous
Alfentanil
Sufentanil
Fentanyl
Propofol