The secretory nature of the lesion of carrot cell variant ts11, rescuable by endochitinase

Planta. 1997;203(3):381-9. doi: 10.1007/s004250050204.

Abstract

The carrot cell variant ts11 is unable to form somatic embryos at the non-permissive temperature of 32 degrees C, but the block can be overcome by the addition of a 32-kDa acidic endochitinase to the medium. In this work we conducted a cyto-histological analysis of the blocked embryo forms. The morphology of the endomembrane system is altered; in particular, the ER is dilated and may show electron-dense precipitates and continuity with the plasma membrane. These morphological alterations do not occur in the presence of externally-added endochitinase. We also noticed modifications of the culture medium that are probably related to the morphological observations: the total amount of secreted proteins is reduced and pulse-chase experiments revealed that, compared with wild-type cells, the secretion of major polypeptides is reduced while new minor polypeptides are secreted. Western blot analysis revealed the presence of the binding protein BiP, a resident of the ER and of glutamine synthase, a cytosolic protein, in the medium of ts11 but not wild-type cells. These results indicate that ts11 is altered in the secretory pathway but do not clarify the role of endochitinase.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cells, Cultured
  • Chitinases / metabolism*
  • Chitinases / pharmacology
  • Daucus carota / genetics
  • Daucus carota / physiology*
  • Daucus carota / ultrastructure
  • Genetic Variation
  • Microscopy, Electron
  • Seeds / physiology
  • Seeds / ultrastructure*

Substances

  • Chitinases