Bioavailability of hydrochlorothiazide from pellets, made by extrusion/spheronisation, containing polyethylene glycol 400 as a dissolution enhancer

Pharm Res. 1997 Nov;14(11):1644-6. doi: 10.1023/a:1012151006742.

Authors

C Vervaet¹, J P Remon

Affiliation

¹ Laboratory of Pharmaceutical Technology, University of Gent, Belgium.

PMID: 9434288
DOI: 10.1023/a:1012151006742

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adjuvants, Pharmaceutic / pharmacokinetics*
Administration, Oral
Adult
Biological Availability
Cross-Over Studies
Drug Compounding
Drug Implants
Humans
Hydrochlorothiazide / blood
Hydrochlorothiazide / pharmacokinetics*
Male
Middle Aged
Polyethylene Glycols / pharmacokinetics*
Random Allocation
Solubility

Substances

Adjuvants, Pharmaceutic
Drug Implants
Hydrochlorothiazide
Polyethylene Glycols