Learning-induced dynamic receptive field changes in primary auditory cortex of the unanaesthetized Mongolian gerbil

J Comp Physiol A. 1997 Dec;181(6):685-96. doi: 10.1007/s003590050150.

Abstract

Learning-induced changes of the spectro-temporal characteristics of primary auditory cortex (AI) units were studied by response plane analysis of recordings from the AI in unanaesthetized Mongolian gerbils. Using response planes obtained prior to and after auditory discrimination training bins of significant change were identified and their spectro-temporal distribution was studied. Bins of significant changes were generally found to be distributed over the entire spectro-temporal receptive field but occurred most frequently within the first 100 ms of response in the spectral neighbourhood (1.5 octaves) of the frequency of the reinforced conditioned stimulus. Training-induced response decreases occurred early after 10 ms for reinforced conditioned tones and tones in the frequency neighbourhood. Response increases occurred so early only for non-reinforced tones in the neighbourhood of the reinforced frequency and occurred later (after 40 ms) for the reinforced tones. The results are discussed in the light of dynamic disinhibition.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Auditory Cortex / physiology*
  • Behavior, Animal / physiology
  • Conditioning, Classical / physiology
  • Gerbillinae / physiology*
  • Heart Rate / physiology
  • Learning / physiology*
  • Male
  • Neuronal Plasticity / physiology