Fetal calf serum decreases CYP3A induction in rat but not in dog or human hepatocyte cultures

Biochem Soc Trans. 1997 Nov;25(4):S607. doi: 10.1042/bst025s607.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Aryl Hydrocarbon Hydroxylases*
  • Blood
  • Cattle
  • Cells, Cultured
  • Culture Media
  • Cytochrome P-450 CYP3A
  • Cytochrome P-450 Enzyme System / biosynthesis*
  • Dexamethasone / pharmacology
  • Dogs
  • Enzyme Induction / drug effects
  • Female
  • Fetus
  • Humans
  • Liver / cytology
  • Liver / enzymology*
  • Oxidoreductases, N-Demethylating / biosynthesis*
  • Rats
  • Rats, Sprague-Dawley
  • Rifampin / pharmacology

Substances

  • Culture Media
  • Dexamethasone
  • Cytochrome P-450 Enzyme System
  • Aryl Hydrocarbon Hydroxylases
  • Cytochrome P-450 CYP3A
  • Oxidoreductases, N-Demethylating
  • Rifampin