Lung fibrosis induced by paclitaxel

Support Care Cancer. 1998 Jan;6(1):68-71. doi: 10.1007/s005200050135.

Abstract

In a 59-year old man with IIIb non-small-cell lung cancer, a combined treatment with paclitaxel and carboplatin was used for potentiation of radiotherapy. The patient was alive and free of neoplastic disease 14 months after the end of treatment but irreversible lung fibrosis had developed.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Carboplatin / therapeutic use
  • Carcinoma, Non-Small-Cell Lung / drug therapy*
  • Carcinoma, Non-Small-Cell Lung / radiotherapy
  • Chemotherapy, Adjuvant
  • Humans
  • Lung Neoplasms / drug therapy*
  • Lung Neoplasms / radiotherapy
  • Male
  • Middle Aged
  • Paclitaxel / adverse effects*
  • Paclitaxel / therapeutic use
  • Pulmonary Fibrosis / chemically induced*
  • Pulmonary Fibrosis / diagnosis
  • Radiation-Sensitizing Agents / adverse effects*
  • Radiation-Sensitizing Agents / therapeutic use
  • Tomography, X-Ray Computed

Substances

  • Radiation-Sensitizing Agents
  • Carboplatin
  • Paclitaxel