Abstract
We report a patient with diffuse pulmonary hemorrhage after streptokinase therapy for acute myocardial infarction. Hemoptysis, anemia, fever, jaundice, progressive bilateral pulmonary infiltrates and severe acute respiratory failure were observed. The patient required mechanical ventilation and recovered successfully. An immunological reaction to a highly antigenic agent such as streptokinase is considered in the pathogenesis of this complication.
MeSH terms
-
Bronchoalveolar Lavage
-
Fibrinolytic Agents / adverse effects*
-
Fibrinolytic Agents / therapeutic use
-
Follow-Up Studies
-
Hemoptysis / chemically induced
-
Hemorrhage / chemically induced*
-
Hemorrhage / diagnosis
-
Humans
-
Lung Diseases / chemically induced*
-
Lung Diseases / diagnosis
-
Male
-
Middle Aged
-
Myocardial Infarction / complications
-
Myocardial Infarction / drug therapy*
-
Streptokinase / adverse effects*
-
Streptokinase / therapeutic use
-
Thrombolytic Therapy / adverse effects*
Substances
-
Fibrinolytic Agents
-
Streptokinase