Mycosis fungoides with focal segmental glomerular sclerosis and nephrotic syndrome

J C Cather; C Jackow; J Yegge; F Hagemeister; M Duvic

doi:10.1016/s0190-9622(98)70569-9

Mycosis fungoides with focal segmental glomerular sclerosis and nephrotic syndrome

J Am Acad Dermatol. 1998 Feb;38(2 Pt 2):301-5. doi: 10.1016/s0190-9622(98)70569-9.

Authors

J C Cather¹, C Jackow, J Yegge, F Hagemeister, M Duvic

Affiliation

¹ Division of Medical Specialties, University of Texas Medical School, Houston, USA.

PMID: 9486702
DOI: 10.1016/s0190-9622(98)70569-9

Abstract

Cutaneous T-cell lymphoma includes mycosis fungoides and the leukemic variant, Sézary syndrome. We report the first two cases of focal segmental glomerulosclerosis in patients with cutaneous T-cell lymphoma, with nephrotic range proteinuria and review the literature on renal disease coexisting with cutaneous T-cell lymphoma. We hypothesize that glomerular injury in cutaneous T-cell lymphoma may be related to interleukin-2.

Publication types

Case Reports
Research Support, Non-U.S. Gov't
Review

MeSH terms

Biopsy
Combined Modality Therapy
Glomerulosclerosis, Focal Segmental / diagnosis*
Glomerulosclerosis, Focal Segmental / therapy
Humans
Kidney / pathology
Male
Middle Aged
Mycosis Fungoides / diagnosis*
Mycosis Fungoides / therapy
Nephrotic Syndrome / diagnosis*
Nephrotic Syndrome / therapy
Proteinuria / diagnosis
Proteinuria / therapy
Scalp / pathology
Skin Neoplasms / diagnosis*
Skin Neoplasms / therapy