[Propofol and sevoflurane--a comparison of anesthesia for laryngomicrosurgery]

Masui. 1998 Feb;47(2):168-73.
[Article in Japanese]

Abstract

Laryngomicrosurgery has some special characteristics. It is under much stress such as intubation and direct laryngoscopy during a short operation time. Therefore both adequate anesthesia and quick recovery are needed. Thirty three ASA physical status I patients for laryngomicrosurgery were randomly assigned to receive either anesthesia with propofol and small dose of fentanyl (Group P) or anesthesia with thiopental and sevoflurane (Group S). Group P was induced with propofol 2-3 mg.kg-1 and fentanyl 0.1 mg and maintained with propofol 6 mg.kg-1.h-1 (from 10 mg.kg-1.h-1 by 2 mg.kg-1.h-1 decrement in interval of 10 minutes). No intravenous analgesic was added. Group S was induced with thiopental 4 -5 mg.kg-1 and maintained with sevoflurane 2-3%. We compared emergence time and the state of recovery 5 minutes after extubation and 5 minutes after entering the recovery room. There was no episode of inadequate anesthetic state in both groups. The emergence time was significantly shorter in Group P than in Group S. The state of recovery was much better in Group P compared with Group S in both 5 minutes after extubation and 5 minutes after entering the recovery room. Therefore, anesthesia with propofol and small dose of fentanyl at induction is more adequate compared with anesthesia with sevoflurane in laryngomicrosurgery.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Anesthesia Recovery Period*
  • Anesthesia, General*
  • Anesthetics, Inhalation*
  • Anesthetics, Intravenous*
  • Endoscopy
  • Female
  • Fentanyl
  • Humans
  • Laryngectomy*
  • Laryngoscopy
  • Male
  • Methyl Ethers*
  • Microsurgery*
  • Middle Aged
  • Otorhinolaryngologic Surgical Procedures
  • Propofol*
  • Sevoflurane
  • Thiopental
  • Time Factors

Substances

  • Anesthetics, Inhalation
  • Anesthetics, Intravenous
  • Methyl Ethers
  • Sevoflurane
  • Thiopental
  • Fentanyl
  • Propofol