Nongenomic effects of neurosteroids

Gynecol Endocrinol. 1998 Feb;12(1):61-7. doi: 10.3109/09513599809024971.

Abstract

This review summarizes the current knowledge about the synthesis, the mechanism of action, and the effects of neurosteroids in the central nervous system. Particular attention is paid to the nongenomic actions of neurosteroids, which are discussed in relation to their clinical relevance for physiological and pathological states.

Publication types

  • Review

MeSH terms

  • Anesthetics / metabolism
  • Animals
  • Anti-Anxiety Agents / metabolism
  • Anticonvulsants / metabolism
  • Behavior / physiology
  • Brain / metabolism
  • Brain / physiology*
  • Calcium / metabolism
  • Cognition / physiology
  • Female
  • Humans
  • Ovulation / physiology
  • Premenstrual Syndrome / physiopathology
  • Receptors, GABA-A / physiology
  • Receptors, N-Methyl-D-Aspartate / physiology
  • Steroids / biosynthesis*
  • Steroids / metabolism
  • Steroids / physiology
  • Stress, Physiological / physiopathology

Substances

  • Anesthetics
  • Anti-Anxiety Agents
  • Anticonvulsants
  • Receptors, GABA-A
  • Receptors, N-Methyl-D-Aspartate
  • Steroids
  • Calcium