Isolation of a new member of DnaJ-like heat shock protein 40 (Hsp40) from human liver

K L Hoe; M Won; K S Chung; Y J Jang; S B Lee; D U Kim; J W Lee; J H Yun; H S Yoo

doi:10.1016/s0167-4838(97)00207-0

Isolation of a new member of DnaJ-like heat shock protein 40 (Hsp40) from human liver

Biochim Biophys Acta. 1998 Mar 3;1383(1):4-8. doi: 10.1016/s0167-4838(97)00207-0.

Authors

K L Hoe¹, M Won, K S Chung, Y J Jang, S B Lee, D U Kim, J W Lee, J H Yun, H S Yoo

Affiliation

¹ Cell Cycle and Signal Research Unit, Korea Research Institute of Bioscience and Biotechnology, Taejon, South Korea.

PMID: 9546042
DOI: 10.1016/s0167-4838(97)00207-0

Abstract

A new member of Hsp40, HLJ1, consisting of 337 amino acids, was cloned from a human liver cDNA library. The deduced amino acid sequence of HLJ1 has an 84% homology (69% identity) with that of HDJ-1 isolated from human placenta. Northern analysis showed that expression of the HLJ1 gene is heat-inducible and its transcription shows some degree of preference in heart, skeletal muscle, and pancreas.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Base Sequence
Cloning, Molecular
Gene Library
HSP40 Heat-Shock Proteins
Heat-Shock Proteins / isolation & purification*
Humans
Liver / chemistry*
Molecular Sequence Data
Placenta / chemistry
Sequence Homology, Amino Acid

Substances

DNAJB1 protein, human
DNAJB4 protein, human
HSP40 Heat-Shock Proteins
Heat-Shock Proteins

Associated data

GENBANK/U40992