Severe knee pain as the single symptom of CMV infection in acute ulcerative colitis treated with cyclosporine

Inflamm Bowel Dis. 1998 Feb;4(1):27-8. doi: 10.1097/00054725-199802000-00005.

Abstract

We describe a case of systemic cytomegalovirus (CMV) infection in an ulcerative colitis patient admitted to the hospital for an acute flare-up of his colitis. He was treated with combination immunosuppressive therapy including i.v. cyclosporine and corticosteroids and PO azathioprine. Severe bilateral stabbing knee pain was the only manifestation of CMV disease, which quickly responded to adequate antiviral therapy.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adult
  • Anti-Inflammatory Agents / therapeutic use
  • Azathioprine / therapeutic use
  • Colitis, Ulcerative / complications
  • Colitis, Ulcerative / drug therapy*
  • Cyclosporine / therapeutic use
  • Cytomegalovirus / drug effects*
  • Cytomegalovirus Infections / complications
  • Cytomegalovirus Infections / diagnosis*
  • Drug Therapy, Combination
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Knee*
  • Male
  • Methylprednisolone / therapeutic use
  • Pain*

Substances

  • Anti-Inflammatory Agents
  • Immunosuppressive Agents
  • Cyclosporine
  • Azathioprine
  • Methylprednisolone