Update of the gene discovery program in Schistosoma mansoni with the expressed sequence tag approach

E M Rabelo; G R Franco; V A Azevedo; H B Pena; T M Santos; W S Meira; N A Rodrigues; J M Ortega; S D Pena

doi:10.1590/s0074-02761997000500012

Update of the gene discovery program in Schistosoma mansoni with the expressed sequence tag approach

Mem Inst Oswaldo Cruz. 1997 Sep-Oct;92(5):625-9. doi: 10.1590/s0074-02761997000500012.

Authors

E M Rabelo¹, G R Franco, V A Azevedo, H B Pena, T M Santos, W S Meira, N A Rodrigues, J M Ortega, S D Pena

Affiliation

¹ Departamento de Parasitologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brasil.

PMID: 9566229
DOI: 10.1590/s0074-02761997000500012

Abstract

Continuing the Schistosoma mansoni Genome Project 363 new templates were sequenced generating 205 more ESTs corresponding to 91 genes. Seventy four of these genes (81%) had not previously been described in S. mansoni. Among the newly discovered genes there are several of significant biological interest such as synaptophysin, NIFs-like and rho-GDP dissociation inhibitor.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Chromosome Mapping
DNA, Helminth*
Genome*
Schistosoma mansoni / genetics*
Sequence Homology, Nucleic Acid*
Sequence Tagged Sites*

Substances

DNA, Helminth