Abstract
The relationships between the skeletal Ca/P ratio (used as an index of bone quality) and structural changes in the bone and skin was studied in inflammatory mediated osteoporosis (IMO). The bone Ca/P ratio in IMO rabbits was significantly lower than in controls. Also, severe alterations were detected at the ultrastructural level in bone and skin collagen fibrils from IMO rabbits.
MeSH terms
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Absorptiometry, Photon
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Animals
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Bone Density*
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Bone and Bones / metabolism*
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Bone and Bones / pathology
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Bone and Bones / ultrastructure
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Calcium / analysis*
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Collagen / metabolism*
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Female
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Gamma Rays
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Inflammation / chemically induced
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Inflammation / pathology
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Inflammation / physiopathology*
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Injections, Subcutaneous
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Magnesium Silicates / administration & dosage
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Osteoporosis / chemically induced
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Osteoporosis / pathology
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Osteoporosis / physiopathology*
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Phosphates / analysis*
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Rabbits
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Reference Values
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Skin / chemistry*
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Skin / pathology
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Skin / ultrastructure
Substances
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Magnesium Silicates
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Phosphates
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Florisil
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Collagen
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Calcium