A study on cholangitis after hepatic portoenterostomy for biliary atresia

Chin Med J (Engl). 1997 May;110(5):335-7.

Abstract

Objective: To investigate the clinical manifestations and factors relating to prognosis in biliary atresia (BA).

Methods: Twenty-four cases were reviewed on clinical manifestations and bile flow after operation. All patients underwent hepatic portoenterostomy.

Results: Twenty-three cases (95%) got bile flow postoperatively. Sixteen (69%) of 23 patients had 27 episodes of cholangitis. There were significant differences (P < 0.05) in the amount and bilirubin concentration of bile flow before and after cholangitis. Cholangitis also affected the life quality of BA patients.

Conclusion: We consider that early finding and prevention of cholangitis can improve the prognosis of BA patients.

MeSH terms

  • Biliary Atresia / surgery*
  • Cholangitis / etiology*
  • Cholangitis / prevention & control
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Portoenterostomy, Hepatic / adverse effects*