Abstract
Amiodarone is an antiarrhythmic drug widely used to treat a variety of supraventricular and ventricular arrhythmias. However its drawback is a very slow elimination and very frequent adverse effects (thyroid, pulmonary, neurologic, ocular, dermatologic, hepatic disorders). We describe a patient who developed a pseudoalcoholic liver disease and a cirrhosis after use of Amiodarone for a long period of time.
MeSH terms
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Amiodarone / adverse effects*
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Amiodarone / pharmacokinetics
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Anti-Arrhythmia Agents / adverse effects*
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Anti-Arrhythmia Agents / pharmacokinetics
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Chemical and Drug Induced Liver Injury / etiology*
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Chemical and Drug Induced Liver Injury / pathology
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Humans
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Liver Cirrhosis / chemically induced*
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Liver Cirrhosis / pathology
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Male
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Metabolic Clearance Rate
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Middle Aged
Substances
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Anti-Arrhythmia Agents
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Amiodarone