The origin of APRT*J. The most common disease-related mutation of APRT gene among Japanese goes back to a prehistoric era

Adv Exp Med Biol. 1998:431:135-9. doi: 10.1007/978-1-4615-5381-6_26.
No abstract available

MeSH terms

  • Adenine Phosphoribosyltransferase / deficiency*
  • Adenine Phosphoribosyltransferase / genetics*
  • Alleles
  • DNA Primers
  • Evolution, Molecular
  • Genotype
  • Geography
  • Homozygote
  • Humans
  • Incidence
  • Japan / epidemiology
  • Korea
  • Mutation
  • Polymerase Chain Reaction
  • Polymorphism, Single-Stranded Conformational*
  • Purine-Pyrimidine Metabolism, Inborn Errors / enzymology
  • Purine-Pyrimidine Metabolism, Inborn Errors / epidemiology
  • Purine-Pyrimidine Metabolism, Inborn Errors / genetics*
  • Taiwan

Substances

  • DNA Primers
  • Adenine Phosphoribosyltransferase