Identification of antibiotics of iturin group in various strains of Bacillus subtilis

J Antibiot (Tokyo). 1978 Apr;31(4):284-8. doi: 10.7164/antibiotics.31.284.

Abstract

Thirty eight strains of B. subtilis were tested for the presence of antifungal antibiotics of the iturin group. The characterization of these antibiotics was made on the basis of: antifungal activity against P. chrysogenum, isolation and purification of the active substance, quantitative analysis of alpha-aminoacids and identification of the liposoluble dipeptide obtained by partial hydrolysis. The only antibiotics of the iturin group found were: iturin A, mycosubtilin and bacillomycin L.

MeSH terms

  • Antifungal Agents / analysis
  • Antifungal Agents / biosynthesis*
  • Antifungal Agents / pharmacology
  • Bacillus subtilis / metabolism*
  • Hydrolysis
  • Penicillium chrysogenum / drug effects
  • Peptides, Cyclic

Substances

  • Antifungal Agents
  • Peptides, Cyclic
  • iturin A