Abstract
Eleven days after double lung transplantation for cystic fibrosis, an 18-year-old patient developed a disseminated Fusarium solani infection with tricuspid valve endocarditis. This infection occurred under fluconazole and immunosuppressive therapy with cyclosporin, prednisone and azathioprine, with a normal leucocyte count. Liposomal amphotericin B allowed blood culture negativation. The patient died from a bacterial septic shock.
MeSH terms
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Adolescent
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Amphotericin B / therapeutic use
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Antifungal Agents / therapeutic use
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Cystic Fibrosis / surgery
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Endocarditis / microbiology*
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Female
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Fungemia / drug therapy
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Fungemia / microbiology*
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Fusarium / drug effects
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Fusarium / isolation & purification*
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Humans
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Immunocompromised Host
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Liposomes
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Lung Transplantation / adverse effects*
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Mycoses / drug therapy
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Mycoses / microbiology*
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Opportunistic Infections / drug therapy
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Opportunistic Infections / microbiology*
Substances
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Antifungal Agents
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Liposomes
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Amphotericin B