Translocation (3;13)(q27;q14): a nonrandom and probably secondary structural change in non-Hodgkin lymphomas

Cancer Genet Cytogenet. 1998 Jun;103(2):140-3. doi: 10.1016/s0165-4608(97)00391-9.

Abstract

Three cases of (3;13)(q27;q14) translocation observed in different histological types of non-Hodgkin lymphomas (NHLs) are reported here. This new recurring translocation in NHL was secondary in at least two of the patients because it was associated with another specific change [i.e., t(8;14) (q24;q32) in Burkitt lymphoma and t(14;18)(q32;q21) in typical follicular lymphoma]. In two of the cases for which molecular analysis was performed, a rearrangement of the LAZ-3/BCK-6 gene was found.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Burkitt Lymphoma / genetics
  • Chromosome Aberrations / genetics*
  • Chromosome Disorders
  • Chromosomes, Human, Pair 13 / genetics*
  • Chromosomes, Human, Pair 3 / genetics*
  • Female
  • Gene Rearrangement / genetics
  • Humans
  • Karyotyping
  • Lymphoma, Follicular / genetics
  • Lymphoma, Large B-Cell, Diffuse / genetics
  • Lymphoma, Non-Hodgkin / genetics*
  • Translocation, Genetic / genetics*