Common polymorphisms in genes encoding the human mineralocorticoid receptor and the human amiloride-sensitive sodium channel

M Ludwig; U Bolkenius; L Wickert; F Bidlingmaier

doi:10.1016/s0960-0760(97)00195-7

Common polymorphisms in genes encoding the human mineralocorticoid receptor and the human amiloride-sensitive sodium channel

J Steroid Biochem Mol Biol. 1998 Mar;64(5-6):227-30. doi: 10.1016/s0960-0760(97)00195-7.

Authors

M Ludwig¹, U Bolkenius, L Wickert, F Bidlingmaier

Affiliation

¹ Department of Clinical Biochemistry, University of Bonn, Germany.

PMID: 9618022
DOI: 10.1016/s0960-0760(97)00195-7

Abstract

We have examined the human mineralocorticoid receptor gene and the genes encoding the three subunits of the human amiloride-sensitive epithelial sodium channel. Eight new common polymorphisms were identified in these genes which may be useful in genotyping and linkage analysis.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amiloride / pharmacology*
DNA Primers / chemistry
Female
Genetic Linkage / genetics
Genotype
Humans
Kidney / physiology*
Male
Molecular Sequence Data
Polymorphism, Genetic / genetics*
Pseudohypoaldosteronism / physiopathology
Receptors, Mineralocorticoid / genetics*
Sequence Analysis, DNA
Sodium Channels / genetics*
White People

Substances

DNA Primers
Receptors, Mineralocorticoid
Sodium Channels
Amiloride

Associated data

GENBANK/X97925
GENBANK/Z92978
GENBANK/Z92979
GENBANK/Z92980
GENBANK/Z92981