Cancrum oris (noma) in a patient with acute lymphoblastic leukaemia. A complication of chemotherapy induced neutropenia

D C Brady-West; L Richards; J Thame; F Moosdeen; A Nicholson

Cancrum oris (noma) in a patient with acute lymphoblastic leukaemia. A complication of chemotherapy induced neutropenia

West Indian Med J. 1998 Mar;47(1):33-4.

Authors

D C Brady-West¹, L Richards, J Thame, F Moosdeen, A Nicholson

Affiliation

¹ Department of Pathology, and Microbiology, University of the West Indies, Mona, Jamaica.

PMID: 9619095

Abstract

Cancrum oris (noma) has been most commonly described in malnourished debilitated children with poor oral hygiene following systemic childhood infections such as measles, pertussis or scarlet fever. We describe a patient who developed this condition during a period of profound neutropenia following cytotoxic chemotherapy for acute lymphoblastic leukaemia.

Publication types

Case Reports

MeSH terms

Adult
Antineoplastic Combined Chemotherapy Protocols / adverse effects*
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Female
Gangrene
Humans
Klebsiella Infections / chemically induced
Klebsiella Infections / pathology
Klebsiella pneumoniae
Leukemia-Lymphoma, Adult T-Cell / drug therapy*
Leukemia-Lymphoma, Adult T-Cell / pathology
Lip / pathology
Mouth Mucosa / pathology
Neutropenia / chemically induced*
Neutropenia / pathology
Noma / chemically induced*
Noma / pathology
Pseudomonas Infections / chemically induced
Pseudomonas Infections / pathology
Pseudomonas aeruginosa
Remission Induction
Staphylococcal Infections / chemically induced
Staphylococcal Infections / pathology