Abstract
The seroprevalence of human herpesvirus 8 (HHV-8) in the Swiss population was investigated. By enzyme-linked immunosorbent assay, sera reactive to the recombinant HHV-8 antigen orf 65.2 were found in 24% of human immunodeficiency virus (HIV)-positive patients without and in 92% of HIV-positive patients with Kaposi's sarcoma. Surprisingly, 20% of homosexual HIV-negative men, versus only 7% of heterosexual HIV-negative individuals and 5% of blood donors, had antibodies to HHV-8.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
AIDS-Related Opportunistic Infections / epidemiology
-
Adult
-
Aged
-
Antibodies, Viral / blood*
-
Antigens, Viral / immunology
-
Cohort Studies
-
Enzyme-Linked Immunosorbent Assay
-
Female
-
HIV Seronegativity
-
Herpesviridae Infections / epidemiology*
-
Herpesvirus 8, Human / immunology*
-
Homosexuality, Male*
-
Humans
-
Male
-
Middle Aged
-
Prevalence
-
Sarcoma, Kaposi / epidemiology
-
Sarcoma, Kaposi / immunology
-
Switzerland / epidemiology
Substances
-
Antibodies, Viral
-
Antigens, Viral