Effect of temperature on motor responses in organophosphate intoxication

Muscle Nerve. 1998 Jul;21(7):958-60. doi: 10.1002/(sici)1097-4598(199807)21:7<958::aid-mus19>3.0.co;2-m.

Abstract

We studied the effect of temperature on median motor responses in a 41-year-old man with organophosphate intoxication. At 32 degrees C, a normal amplitude compound motor action potential (CMAP) and a smaller spontaneous repetitive discharge (SRMAP) were present. With warming to 39 degrees C, the CMAP amplitude decreased 20%, while the SRMAP amplitude decreased 33%. With cooling to 14 degrees C, the CMAP amplitude decreased 9%, while the SRMAP became unobtainable. Possible mechanisms for these findings are discussed.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Cold Temperature*
  • Evoked Potentials, Motor / physiology*
  • Hot Temperature*
  • Humans
  • Insecticides / toxicity*
  • Male
  • Median Nerve / physiology
  • Motor Neurons / physiology
  • Muscle, Skeletal / innervation
  • Muscle, Skeletal / physiology
  • Organophosphorus Compounds*
  • Polyneuropathies / chemically induced*
  • Polyneuropathies / physiopathology

Substances

  • Insecticides
  • Organophosphorus Compounds